Description
Acetonitrile 99.9% HPLC – Identification of Product
Chemical Code: CHE-A9
Chemical Name: Acetonitrile
Chemical Grade: HPLC
Chemical Formula: CH₃CN
Chemical Weight: 41.05 g/mol
CAS No: 75-05-8
Chemical Synonyms: Methyl Cyanide, ACN.
Acetonitrile 99.9% HPLC – Hazards Identification
REACH No: 01-2119471307-38-XXXX
Signal Word: Danger
Supplemental Hazard Information:
Additional Hazard Information: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher.
Acetonitrile 99.9% HPLC – Hazards statements
H225 – Highly flammable liquid and vapour.
H302 + H312 + H332 – Harmful if swallowed, in contact with skin or if inhaled.
H319 – Causes serious eye irritation.
Acetonitrile 99.9% HPLC – Precautionary statements
P210 – Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P280 – Wear protective gloves/ protective clothing.
P301 + P312 + P330 – IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P302 + P352 + P312 – IF ON SKIN: Wash with plenty of water. Call a POISON CENTER/doctor if you feel unwell.
P304 + P340 + P312 – IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P305 + P351 + P338 – IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Acetonitrile 99.9% HPLC – Chemical Composition
Chemical Formula: CH₃CN
EC No 1272/2008: 01-2119471307-38-XXXX
Acetonitrile 99.9% HPLC – First Aid Measures
General Advice: Consult a physician. Show this safety data sheet to the doctor in attendance.
If: Inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
If: Skin Contact: Wash off with soap and plenty of water. Consult a physician.
If: Eye Contac: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If: Swallowed: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Important Symptoms: The most important known symptoms and effects are described in the labelling section.
Immediate Medical Attention: No Data Available
Firefighting Measures
Extinguishing Media: Use Water spray, Alcohol-resistant foam, Dry chemical or Carbon Dioxide.
Hazards Arising: Carbon Oxides, Nitrogen Oxides
Advice for Firefighters: Wear self-contained breathing apparatus for firefighting if necessary.
Info for Firefighting: Use water spray to cool unopened containers.Accidental Release Measures
Personal Precautions: Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Ensure adequate ventilation.
Remove all sources of ignition.
Evacuate personnel to safe areas.
Beware of vapours accumulating to form explosive concentrations.
Vapours can accumulate in low areas.
Enviromental Precautions: Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Method for Containment: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations.
Handling and Storage
Personal Precautions: Avoid contact with skin and eyes.
Avoid inhalation of vapour or mist.
Keep away from sources of ignition – No smoking.
Take measures to prevent the build up of electrostatic charge.
Enviromental Precautions: Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Exposure Controls | Personal Protection
Derived No Effect Level (DNEL)
Workers | Application Area | Exposure Routes | Health Effect | Value
Workers – Inhalation – Acute local effects – 68 mg/m³
Workers – Inhalation – Acute systemic effects – 68 mg/m³
Workers – Skin contact – Long-term systemic effects – 32.2mg/kg BW/d
Workers – Inhalation – Long-term local effects – 68 mg/m³
Workers – Inhalation – Long-term systemic effects – 68 mg/m³
Consumers | Application Area | Exposure Routes | Health Effect | Value
Consumers – Inhalation – Acute local effects – 220 mg/m³
Consumers – Inhalation – Acute systemic effects – 22 mg/m³
Consumers – Inhalation – Long-term systemic effects – 4.8 mg/m³
Predicted No Effect Concentration (PNEC)





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